離線純水TOC分析儀  總有機(jī)碳分析儀是北京北廣精儀公司自主研發(fā)的高精度總有機(jī)碳分析儀器。產(chǎn)品使用電導(dǎo)率差值檢測技術(shù)，檢測精度高，響應(yīng)時間短。產(chǎn)品符合國家法規(guī)和標(biāo)準(zhǔn)，可滿足制藥用水、注射用水、超純水和去離子水的在線及離線的檢測要求。

離線純水TOC分析儀  參數(shù)：

測試工序的流程

TOC 分析儀的測試工作方式為自動化進(jìn)行。測試人員需要做好測試前的準(zhǔn)備工

作，在具體測試過程中不需要調(diào)整和值守。 

TOC 分析儀的測試項目包括：

1） 在線分析 ；

2） 離線分析 ；

3） 系統(tǒng)適應(yīng)性驗證；

4） 零點校準(zhǔn) 。

儀器校準(zhǔn)

‘儀器校準(zhǔn)’主要包括兩部分內(nèi)容，一是儀器的零點校準(zhǔn)；

二是藥典里規(guī)定的儀器必須滿足的系統(tǒng)適應(yīng)性試驗。這兩項測試功能的進(jìn)樣方式都采用手動確認(rèn)的模式。該部分還設(shè)有一個管路沖洗的功能，用于管路的快速清洗，此功能大大縮短了管路清洗的時間。

使用與操作方法

開始檢測并計入檢測次數(shù)，檢測完畢后顯示最后一次檢測結(jié)果，其中幾次檢測的結(jié)果均自動保存在查詢記錄當(dāng)中。檢測次數(shù)的設(shè)置方式為：用“選擇”鍵移動光標(biāo)，用“設(shè)置”鍵修改數(shù)字，按“確定”鍵進(jìn)行確認(rèn)，進(jìn)入分析界面。先進(jìn)行四次沖洗過程

易耗品更換周期

UV燈和蠕動泵管可以從本公司購買。UV燈為185nm、254nm雙波長紫外燈，蠕動泵管為進(jìn)口泵管，具有高品質(zhì)和良好的穩(wěn)定性。易耗品更換周期參考表5.1。

表5.1  易耗品維護(hù)/更換表

二氧化碳傳感器

儀器上安裝有兩個二氧化碳傳感器，由電導(dǎo)率傳感器和溫度傳感器組成。電導(dǎo)率測量采用雙精度技術(shù)，可以實現(xiàn)自動校準(zhǔn)和溫度補(bǔ)償。TIC傳感器用于檢測未經(jīng)氧化的水樣中二氧化碳濃度，同時檢測水樣的電導(dǎo)率值；TC傳感器用于檢測水樣本身含有的二氧化碳和水樣中有機(jī)物經(jīng)分解后產(chǎn)生的二氧化碳濃度的總和。

主要特征:

1、高精度、高靈敏度，操作簡單。

2、人性化操作界面，有一鍵運行功能，自動管路清洗功能。

3、高性能CPU，觸摸屏設(shè)計，超大640*480點陣真彩顯示器。

4、不用拆開機(jī)箱更換UV燈和泵管。

5、檢測上限可設(shè)定，自動上限報警功能。

6、具有RS232數(shù)據(jù)接口，歷史數(shù)據(jù)可存儲6個月。

7、離線檢測和在線檢測可選配。

8、具有打印功能

離線檢測

離線檢測時，儀器可從樣品瓶或其它沒有壓力的容器直接取樣。儀器管路沖洗和儀器校準(zhǔn)應(yīng)在離線狀態(tài)操作。若樣品中有不可溶性微粒，應(yīng)經(jīng)過濾膜（孔徑60μm或更?。┻^濾后進(jìn)入儀器，以防止樣品中的微粒阻塞儀器。儀器的進(jìn)樣管為1/16英寸的Teflon管，經(jīng)蠕動泵抽進(jìn)管路中的水樣流速約為0.5 ml/min。

零點校準(zhǔn)

儀器校準(zhǔn)的目的是為了減小傳感器的零點漂移，并對其測試曲線進(jìn)行修訂，對于保證儀器測試結(jié)果的準(zhǔn)確性有非常重要的意義。

校準(zhǔn)周期可以根據(jù)具體使用情況而定，建議更換紫外燈或儀器使用半年以后校準(zhǔn)一次。出現(xiàn)數(shù)據(jù)分析的結(jié)果偏差較大時，也可進(jìn)行校驗。

儀器在校準(zhǔn)過程過程中，將用到兩種標(biāo)準(zhǔn)液，一種是總有機(jī)碳低于0.1ppm，電導(dǎo)率低于 1.0μs/cm（25℃）的高純水作為零點水；另一種是 0.5ppm 的標(biāo)準(zhǔn)蔗糖溶液。

a) 零點水和標(biāo)準(zhǔn)溶液要采用密閉容器內(nèi)盛放，容器的頂空要盡量小，密封口打開后要盡快測試。

b) 配制校準(zhǔn)溶液之前，蔗糖標(biāo)準(zhǔn)品必須在 105℃（221?F）環(huán)境下干燥至恒重。

低濃度高純水在空氣中暴露超過一小時，會因溶解了空氣中的二氧化碳而使電導(dǎo)率值明顯增大。

二氧化碳測量循環(huán)

儀器每4分鐘檢測得出一個數(shù)據(jù)（包括TOC值和電導(dǎo)率值），在4分鐘的測量循環(huán)中TC和TIC是獨立檢測的。

更換UV 燈

更換UV 燈時，須小心操作，以免損壞燈管及其周圍的螺旋狀石英管。

給客戶提供新UV 燈管時，附送一雙手套供安裝時使用，避免在 UV 燈管表面和螺

旋狀石英管表面留下指紋。指紋會吸收UV 光線、降低氧化反應(yīng)器的氧化性能。同時

在安裝新的UV 燈管之前可以使用乙醇去除指紋和污垢，保證 UV 燈表面的透光率。

更換UV 燈具體操作：

○1 關(guān)閉主電源開關(guān)，拔去電源線。

○2 將儀器機(jī)箱后蓋板的螺釘擰開，打開后蓋板。

○3 拔掉連接燈管的電源線插頭，并檸松燈管座的鎖緊螺母，慢慢抽出燈管。

○4 換上新燈管并調(diào)整燈管在螺旋石英管中的有效位置，擰緊鎖緊螺母。

○5 插好燈管的電源線插頭并將機(jī)箱后蓋板螺絲擰緊，更換結(jié)束。

更換以上部件時存在問題可聯(lián)系儀器廠家解決。

The total organic carbon analyzer is a high-precision total organic carbon analysis instrument independently developed by Beijing Beiguang Jingyi Company. The product uses conductivity difference detection technology, with high detection accuracy and short response time. The product complies with national regulations and standards, and can meet the online and offline testing requirements for pharmaceutical water, injection water, ultrapure water, and deionized water.

Parameters:

1. Measurement range: 0.01mg/L to 1.000 mg/L

2 Precision?4%

3 Resolution 0.001mg/L

4 Analysis time of 40 minutes

5 response times of 8 minutes

6 detection limit of 0.001mg/L

Sample temperature 1-95℃

8 Power Requirements/Function 220V

9. Repeatability error≤3%

10 display color touch screen

The process of testing process

The testing method of TOC analyzer is automated. Testers need to prepare well before testing

During the specific testing process, there is no need to adjust or be on duty.

The testing items for TOC analyzer include:

1) Online analysis;

2) Offline analysis;

3) System adaptability verification;

4) Zero point calibration.

Instrument calibration

Instrument calibration mainly includes two parts: first, zero point calibration of the instrument;

The second is the system adaptability test that the instruments specified in the pharmacopoeia must meet. The injection method for both testing functions adopts manual confirmation mode. This section also has a pipeline flushing function for quick cleaning of pipelines, which greatly shortens the cleaning time of pipelines.

Usage and operation methods

Start the detection and count the number of detections. After the detection is completed, the last detection result will be displayed, and the results of several detections will be automatically saved in the query record. The way to set the number of detections is to use the "Select" key to move the cursor, use the "Set" key to modify the number, press the "OK" key to confirm, and enter the analysis interface. Perform four flushing processes first

Replacement cycle of consumables

UV lamps and peristaltic pump tubes can be purchased from our company. The UV lamp is a dual wavelength UV lamp with 185nm and 254nm wavelengths, and the peristaltic pump tube is an imported pump tube, which has high quality and good stability. Refer to Table 5.1 for the replacement cycle of consumables.

Table 5.1 Maintenance/Replacement of Consumables

Component Name Replacement Cycle*

UV lamp for 12 months

Peristaltic pump tube for 12 months

Carbon dioxide sensor

There are two carbon dioxide sensors installed on the instrument, consisting of conductivity sensors and temperature sensors. The conductivity measurement adopts dual precision technology, which can achieve automatic calibration and temperature compensation. TIC sensors are used to detect the concentration of carbon dioxide in unoxidized water samples, while also detecting the conductivity value of the water samples; The TC sensor is used to detect the total concentration of carbon dioxide contained in the water sample itself and the carbon dioxide produced by the decomposition of organic matter in the water sample.

Main features:

1. High precision, high sensitivity, and simple operation.

2. Humanized operation interface, with one click operation function and automatic pipeline cleaning function.

3. High performance CPU, touch screen design, large 640 * 480 dot matrix true color display.

4. No need to open the chassis to replace the UV lamp and pump tube.

5. The detection upper limit can be set, with automatic upper limit alarm function.

6. Equipped with RS232 data interface, historical data can be stored for 6 months.

7. Offline detection and online detection are optional.

8. With printing function

Offline detection

When conducting offline testing, the instrument can directly take samples from sample bottles or other containers without pressure. Instrument pipeline flushing and instrument calibration should be operated offline. If there are insoluble particles in the sample, they should be filtered through a membrane with a pore size of 60μAfter filtering (m or smaller), enter the instrument to prevent particles in the sample from blocking the instrument. The sampling tube of the instrument is a 1/16 inch Teflon tube, and the water sample flow rate pumped into the pipeline through a peristaltic pump is about 0.5 ml/min.

Zero calibration

The purpose of instrument calibration is to reduce the zero drift of sensors and revise their test curves, which is of great significance in ensuring the accuracy of instrument test results.

The calibration cycle can be determined based on specific usage conditions. It is recommended to replace the UV lamp or calibrate the instrument after six months of use. When there is a significant deviation in the results of data analysis, verification can also be carried out.

During the calibration process of the instrument, two standard solutions will be used: one with a total organic carbon content below 0.1ppm and a conductivity below 1.0μUsing high-purity water at s/cm (25℃) as zero point water; Another type is a standard sucrose solution of 0.5ppm.

a) Zero point water and standard solution should be stored in a closed container, with the top space of the container as small as possible. After the sealing port is opened, testing should be carried out as soon as possible.

b) Before preparing the calibration solution, the sucrose standard must be dried to a constant weight at 105℃(221?F).

Low concentration high-purity water exposed to air for more than an hour will significantly increase its conductivity due to the dissolution of carbon dioxide in the air.

Carbon dioxide measurement cycle

The instrument detects data every 4 minutes (including TOC and conductivity values), and TC and TIC are independently detected during the 4-minute measurement cycle.

Replace UV lamp

When replacing a UV lamp, be careful to avoid damaging the lamp tube and its surrounding spiral quartz tubes.

When providing new UV tubes to customers, a pair of gloves are included for installation to avoid contact with the surface and screws of the UV tubes

Fingerprints are left on the surface of the spiral quartz tube. Fingerprints absorb UV light and reduce the oxidation performance of the oxidation reactor. At the same time

Before installing a new UV lamp, ethanol can be used to remove fingerprints and dirt, ensuring the transparency of the UV lamp surface.

Specific steps for replacing UV lamps:

Turn off the main power switch and unplug the power cord.

Unscrew the screws on the back cover of the instrument case and open the back cover.

Pull out the power cord plug connecting the lamp tube and loosen the locking nut of the lamp tube holder, slowly pulling out the lamp tube.

Replace the lamp with a new one and adjust the effective position of the lamp in the spiral quartz tube, tighten the locking nut.

Insert the power cord plug of the lamp tube and tighten the screws on the back cover of the chassis, and the replacement is complete.

If there are any problems when replacing the above components, please contact the instrument manufacturer for resolution.